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Human ACTN4 Peptide (KQYERSIVDY) (PEP-096909CQ)

This product is synthetic peptide that is derived from Human ACTN4 (AA 691-700). This peptide sequence corresponds to amino acid residues: KQYERSIVDY.
Specificity
Human
Format
Lyophilized powder
Storage
Store at -20°C
Introduction
Alpha actinins belong to the spectrin gene superfamily which represents a diverse group of cytoskeletal proteins, including the alpha and beta spectrins and dystrophins. Alpha actinin is an actin-binding protein with multiple roles in different cell types. In nonmuscle cells, the cytoskeletal isoform is found along microfilament bundles and adherens-type junctions, where it is involved in binding actin to the membrane. In contrast, skeletal, cardiac, and smooth muscle isoforms are localized to the Z-disc and analogous dense bodies, where they help anchor the myofibrillar actin filaments. This gene encodes a nonmuscle, alpha actinin isoform which is concentrated in the cytoplasm, and thought to be involved in metastatic processes. Mutations in this gene have been associated with focal and segmental glomerulosclerosis.
Alternative Name
Actinin Alpha 4; Focal Segmental Glomerulosclerosis 1; Non-Muscle Alpha-Actinin 4; Alpha-Actinin-4; ACTININ-4; FSGS1; FSGS;
Entrez Gene ID
UniProt ID
Cat PEP-096909CQ
Conjugates
Size
Price $
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