Sign in or Register
  |  

Creative Biolabs has successfully developed SARS, MERS and other anti-viral antibodies in the past to assist scientific research. Facing the difficult COVID-19, Creative Biolabs actively invests in antibody development to assist researchers to better understand the characteristics of 2019-nCoV and drug development. Currently, Creative Biolabs is proud to offer an extensive line of research antibodies to support the study of SARS-CoV-2/COVID-19, several of which were validated using virus-infected cell lysates.

Explore the collections of SARS-CoV-2/COVID-19 antibodies >

Human AFF1 Peptide (RSSDSSSKLAK) (PEP-001441CQ)

This product is synthetic peptide that is derived from Human AFF1 (AA 802-812). This peptide sequence corresponds to amino acid residues: RSSDSSSKLAK.
Specificity
Human
Format
Lyophilized powder
Storage
Store at -20°C
Introduction
This gene encodes a member of the AF4/ lymphoid nuclear protein related to the Fragile X E syndrome (FRAXE) family of proteins, which have been implicated in human childhood lymphoblastic leukemia, fragile chromosome X intellectual disability, and ataxia. It is the prevalent mixed-lineage leukemia fusion gene associated with spontaneous acute lymphoblastic leukemia. Members of this family have three conserved domains: an N-terminal homology domain, an AF4/ lymphoid nuclear protein domain, and a C-terminal homology domain. The protein functions as a regulator of RNA polymerase II-mediated transcription through elongation and chromatin remodeling functions. Through RNA interference screens, this gene has been shown to promote the expression of CD133, a plasma membrane glycoprotein required for leukemia cell survival. Alternative splicing results in multiple transcript variants.
Alternative Name
AF4/FMR2 Family Member 1; ALL1-Fused Gene From Chromosome 4 Protein; Pre-B-Cell Monocytic Leukemia Partner 1; Proto-Oncogene AF4; MLLT2; PBM1; AF4
Entrez Gene ID
UniProt ID
Ask a question We look forward to hearing from you.
0 reviews or Q&As
Loading...
Submit a review Submit a review and you will get a coupon.
0 reviews
Loading...

Please try the standard protocols which include: protocols, troubleshooting and guide.

Click here to view the protocols, troubleshooting and guide.

Cat PEP-001441CQ
Conjugates
Size
Price $
  ADD TO CART
Request bulk or custom quote
Second antibody and isotype control