Synthetic phospho-peptide surrounding the phospho Ser477 of human Che-1
Store at 4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.
AATF was identified on the basis of its interaction with MAP3K12/DLK, a protein kinase known to be involved in the induction of cell apoptosis. This gene product contains a leucine zipper, which is a characteristic motif of transcription factors, and was shown to exhibit strong transactivation activity when fused to Gal4 DNA binding domain. Overexpression of this gene interfered with MAP3K12 induced apoptosis.
Apoptosis Antagonizing Transcription Factor; Rb-Binding Protein Che-1; CHE1; DED; Apoptosis-Antagonizing Transcription Factor; Protein AATF; CHE-1; BFR2;