IHC-P, IHC-Fr, ICC, WB
Mixture of human and hamster drug-resistant whole cells and crude plasma membranes
Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.
The membrane-associated protein encoded by this gene is a member of the superfamily of ATP-binding cassette transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies. This protein is a member of the MDR/TAP subfamily. Members of the MDR/TAP subfamily are involved in multidrug resistance as well as antigen presentation. This gene encodes a full transporter and member of the p-glycoprotein family of membrane proteins with phosphatidylcholine as its substrate. The function of this protein has not yet been determined; however, it may involve transport of phospholipids from liver hepatocytes into bile. Alternative splicing of this gene results in several products of undetermined function.
ATP Binding Cassette Subfamily B Member 4; ATP-Binding Cassette, Sub-Family B (MDR/TAP), Member 4; ATP-Binding Cassette Sub-Family B Member 4; Multidrug Resistance Protein 3; P-Glycoprotein 3; EC 126.96.36.199; MDR3; PGY3; P-Glycoprotein-3/Multiple Drug Resistance-3; Phosphatidylcholine Translocator ABCB4