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Rabbit Anti-ACTN4 Recombinant Antibody (13A151) (CBMAB-0021CQ)

This product is a rabbit antibody that recognizes ACTN4. The antibody 13A151 can be used for immunoassay techniques such as: WB, ICC, IHC, IP.
Host Species
Rabbit
Application
WB, ICC, IHC, IP
Immunogen
Human ACTN4 N-terminal
Antibody Isotype
IgG
Specificity
Human, Mouse, Rat
Clone
13A151
Storage
Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.
Introduction
Alpha actinins belong to the spectrin gene superfamily which represents a diverse group of cytoskeletal proteins, including the alpha and beta spectrins and dystrophins. Alpha actinin is an actin-binding protein with multiple roles in different cell types. Alpha-actinin is highly expressed in the glomerular podocyte, is important in nonmuscle cytoskeletal function, and is upregulated early in the course of some animal models of nephrotic syndrome. Using immunohistochemistry, El-Husseini et al. (2000) showed that rat RNF22 and ACTN4 are expressed in a punctate pattern throughout the cytoplasm and neuritic processes of differentiated PC12 cells. They concluded that the isoform of ACTN4 they identified may act to anchor microfilaments to various cellular structures.
Alternative Name
Actinin, Alpha 4; Focal Segmental Glomerulosclerosis 1; Non-Muscle Alpha-Actinin 4; F-Actin Cross-Linking Protein; Actinin Alpha4 Isoform; ACTININ-4; FSGS1; FSGS
Entrez Gene ID
Human81
Mouse60595
Rat63836
UniProt ID
HumanO43707
MouseP57780
RatQ9QXQ0
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For research use only. Not intended for any clinical use.
Cat CBMAB-0021CQ
Conjugates
Size
Price $
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Second antibody and isotype control