Store at 4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.
Calcium-activated chloride channel (CaCC) which plays a role in transepithelial anion transport and smooth muscle contraction. ANO1 is required for the normal functioning of the interstitial cells of Cajal (ICCs) which generate electrical pacemaker activity in gastrointestinal smooth muscles. ANO1 acts as a major contributor to basal and stimulated chloride conductance in airway epithelial cells and plays an important role in tracheal cartilage development.
Anoctamin 1; Discovered On Gastrointestinal Stromal Tumors Protein 1; Anoctamin 1, Calcium Activated Chloride Channel; Tumor-Amplified And Overexpressed Sequence 2; Oral Cancer Overexpressed 2; Transmembrane Protein 16A; TMEM16A; ORAOV2;