FC, FuncS, IF, IHC-Fr, WB
Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.
AOC3 are expressed on the cell surface and catalyze oxidative deamination of primary amines in a reaction that produces aldehyde, ammonium, and hydrogen peroxide. AOC3 is expressed on the surface of endothelial cells and is involved in leukocyte trafficking between blood and tissues under physiologic and pathologic conditions. The encoded protein is localized to the cell surface, has adhesive properties as well as monoamine oxidase activity, and may be involved in leukocyte trafficking. Alterations in levels of the encoded protein may be associated with many diseases, including diabetes mellitus. A pseudogene of this gene has been described and is located approximately 9-kb downstream on the same chromosome. Alternative splicing results in multiple transcript variants.
Amine Oxidase, Copper Containing 3; Semicarbazide-Sensitive Amine Oxidase; Vascular Adhesion Protein 1; Copper Amine Oxidase; EC 22.214.171.124; VAP-1; HPAO; SSAO; VAP1; Amine Oxidase, Copper Containing 3 (Vascular Adhesion Protein 1); Placenta Copper Monamine Oxidase; EC 1.4.3