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Mouse Anti-APOE Recombinant Antibody (E6D7) (CBMAB-0079CQ)

This product is a mouse antibody that recognizes APOE. The antibody E6D7 can be used for immunoassay techniques such as: ELISA, IF, IHC, IP, WB.
Host Species
Mouse
Application
ELISA, IF, IHC, IP, WB
Immunogen
Synthetic peptide spanning the polymorphic amino acid position 158 of ApoE
Antibody Isotype
IgG1
Specificity
Mouse, Human
Clone
E6D7
Storage
Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.
Introduction
Apolipoprotein E is the recognition site for receptors involved in the clearance of remnants of very low density lipoproteins and chylomicrons. The protein encoded by this gene is a major apoprotein of the chylomicron. It binds to a specific liver and peripheral cell receptor, and is essential for the normal catabolism of triglyceride-rich lipoprotein constituents. ApoE, a main apoprotein of the chylomicron, binds to a specific receptor on liver cells and peripheral cells. The E2 variant binds less readily. Weisgraber et al. showed that human E apoprotein of the E2 form, which contains cysteine (rather than arginine) at both of the 2 variable sites, binds poorly with cell surface receptors, whereas E3 and E4 bind well.
Alternative Name
Apolipoprotein E; APO-E; Alzheimer Disease 2 (APOE*E4-Associated, Late Onset); Apolipoprotein E3; LDLCQ5; LPG; AD2
Entrez Gene ID
Human348
Mouse11816
UniProt ID
HumanP02649
MouseP08226
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For Research Use Only. Not For Clinical Use.
Cat CBMAB-0079CQ
Conjugates
Size
Price $
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Second antibody and isotype control