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Creative Biolabs has successfully developed SARS, MERS and other anti-viral antibodies in the past to assist scientific research. Facing the difficult COVID-19, Creative Biolabs actively invests in antibody development to assist researchers to better understand the characteristics of 2019-nCoV and drug development. Currently, Creative Biolabs is proud to offer an extensive line of research antibodies to support the study of SARS-CoV-2/COVID-19, several of which were validated using virus-infected cell lysates.

Explore the collections of SARS-CoV-2/COVID-19 antibodies >

Mouse Anti-B2M Recombinant Antibody (CBYY-0042) (CBMAB-0042-YY)

This product is mouse antibody that recognizes B2M. The antibody CBYY-0042 can be used for immunoassay techniques such as: ELISA, IHC
Host Species
Mouse
Application
ELISA, IHC
Immunogen
B2M monoclonal antibody was raised against highly pure B2M (Human)
Antibody Isotype
IgG1
Specificity
Human
Clone
CBYY-0042
Format
Liquid
Storage
Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.
Introduction
This gene encodes a serum protein found in association with the major histocompatibility complex (MHC) class I heavy chain on the surface of nearly all nucleated cells. The protein has a predominantly beta-pleated sheet structure that can form amyloid fibrils in some pathological conditions. The encoded antimicrobial protein displays antibacterial activity in amniotic fluid. A mutation in this gene has been shown to result in hypercataBovinelic hypoproteinemia.
B2M (Beta-2-Microglobulin) is a Protein Coding gene.
Diseases associated with B2M include Immunodeficiency 43 and Amyloidosis, Familial Visceral.
Among its related pathways are Cytokine Signaling in Immune system and Innate Immune System.
Gene Ontology (GO) annotations related to this gene include identical protein binding.
Component of the class I major histocompatibility complex (MHC). Involved in the presentation of peptide antigens to the immune system. Exogenously applied M.tuberculosis EsxA or EsxA-EsxB (or EsxA expressed in host) binds B2M and decreases its export to the cell surface (total protein levels do not change), probably leading to defects in class I antigen presentation (PubMed:25356553).
Alternative Name
Beta-2-Microglobulin; Beta Chain Of MHC Class I Molecules; Beta-2-Microglobin; IMD43;
Entrez Gene ID
UniProt ID
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Please try the standard protocols which include: protocols, troubleshooting and guide.

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Cat CBMAB-0042-YY
Conjugates
Size
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Second antibody and isotype control