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Mouse Anti-C8B Recombinant Antibody (CBFYC-0673) (CBMAB-C0727-FY)

This product is mouse antibody that recognizes C8B. The antibody CBFYC-0673 can be used for immunoassay techniques such as: ELISA, IP, WB.
See all C8B antibodies

Summary

Host Animal
Mouse
Specificity
Human
Clone
CBFYC-0673
Antibody Isotype
IgG1
Application
ELISA, IP, WB

Basic Information

Immunogen
Protein purified from Human plasma
Specificity
Human
Antibody Isotype
IgG1
Clonality
Monoclonal
Application Notes
The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Format
Liquid
Buffer
HEPES, 0.01% BSA, 0.15 M NaCl, 50% glycerol
Preservative
0.03% Sodium azide
Concentration
2 mg/mL
Storage
Store at +4°C short term (1-2 weeks). Aliquot and store at-20°C long term. Avoid repeated freeze/thaw cycles.

Target

Full Name
Complement C8 beta chain
Introduction
This gene encodes one of the three subunits of the complement component 8 (C8) protein.
Entrez Gene ID
732
UniProt ID
P07358
Alternative Names
C82
Function
Constituent of the membrane attack complex (MAC) that plays a key role in the innate and adaptive immune response by forming pores in the plasma membrane of target cells.
Biological Process
Complement activation Source: Reactome
Complement activation, alternative pathway Source: UniProtKB-KW
Complement activation, classical pathway Source: UniProtKB-KW
Cytolysis Source: UniProtKB-KW
Immune response Source: ProtInc
Regulation of complement activation Source: Reactome
Cellular Location
Secreted
Involvement in disease
Complement component 8 deficiency, 2 (C8D2): A rare defect of the complement classical pathway associated with susceptibility to severe recurrent infections, predominantly by Neisseria gonorrhoeae or Neisseria meningitidis.
PTM
N-glycosylated; contains one or two bound glycans. Not O-glycosylated.
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For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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