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Mouse Anti-CAPZA3 Recombinant Antibody (CBXC-1606) (CBMAB-C5613-CQ)

This product is a mouse antibody that recognizes CAPZA3. The antibody CBXC-1606 can be used for immunoassay techniques such as: ELISA, WB.
See all CAPZA3 antibodies

Summary

Host Animal
Mouse
Specificity
Human, Rat
Clone
CBXC-1606
Antibody Isotype
IgG2a, κ
Application
ELISA, WB

Basic Information

Immunogen
Partial recombinant corresponding to aa200-300 from human CAPZA3 (NP_201585) with GST tag. MW of the GST tag alone is 26kD
Specificity
Human, Rat
Antibody Isotype
IgG2a, κ
Clonality
Monoclonal
Application Notes
The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Format
Liquid
Buffer
PBS, pH 7.2
Storage
Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.

Target

Full Name
Capping Actin Protein Of Muscle Z-Line Alpha Subunit 3
Introduction
CAPZA3 (Capping Actin Protein Of Muscle Z-Line Alpha Subunit 3) is a Protein Coding gene. Among its related pathways are Endocytosis and Cell cycle_Spindle assembly and chromosome separation. Gene Ontology (GO) annotations related to this gene include actin binding. An important paralog of this gene is CAPZA1.
Entrez Gene ID
Human93661
Rat29324
UniProt ID
HumanQ96KX2
RatQ9WUV6
Alternative Names
Capping Actin Protein Of Muscle Z-Line Alpha Subunit 3; Capping Protein (Actin Filament) Muscle Z-Line, Alpha 3; Germ Cell-Specific Protein 3; CapZ Alpha-3; CP-Alpha-3; Gsg3; Testis Tissue Sperm-Binding Protein Li 73n;
Function
F-actin-capping proteins bind in a Ca2+-independent manner to the fast growing ends of actin filaments (barbed end) thereby blocking the exchange of subunits at these ends. Unlike other capping proteins (such as gelsolin and severin), these proteins do not sever actin filaments. May play a role in the morphogenesis of spermatid (By similarity).
Biological Process
Actin cytoskeleton organization Source: GO_Central
Actin filament organization Source: Ensembl
Antigen processing and presentation of exogenous peptide antigen via MHC class II Source: Reactome
Barbed-end actin filament capping Source: GO_Central
Cytoplasm organization Source: Ensembl
Endoplasmic reticulum to Golgi vesicle-mediated transport Source: Reactome
Spermatid development Source: Ensembl
Cellular Location
Cortical cytoskeleton; F-actin capping protein complex; Cytosol; Nucleus; Membrane; Sperm head
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For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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