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Mouse Anti-CASP9 Recombinant Antibody (CBXC-2486) (CBMAB-C5159-CQ)

This product is a mouse antibody that recognizes CASP9. The antibody CBXC-2486 can be used for immunoassay techniques such as: ELISA, IF, IHC, IP, WB.
Host Animal
Mouse
Application
ELISA, IF, IHC, IP, WB
Antibody Isotype
IgG2b
Cross Reactivity
Human, Mouse, Rat
Clone
CBXC-2486
Storage
Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.
Introduction
This gene encodes a member of the cysteine-aspartic acid protease (caspase) family. Sequential activation of caspases plays a central role in the execution-phase of cell apoptosis. Caspases exist as inactive proenzymes which undergo proteolytic processing at conserved aspartic residues to produce two subunits, large and small, that dimerize to form the active enzyme. This protein can undergo autoproteolytic processing and activation by the apoptosome, a protein complex of cytochrome c and the apoptotic peptidase activating factor 1; this step is thought to be one of the earliest in the caspase activation cascade. This protein is thought to play a central role in apoptosis and to be a tumor suppressor. Alternative splicing results in multiple transcript variants.
Alternative Name
Caspase 9; Caspase 9, Apoptosis-Related Cysteine Peptidase; Protein Phosphatase 1, Regulatory Subunit 56; ICE-Like Apoptotic Protease 6; ICE-LAP6; APAF-3; MCH6; Caspase 9, Apoptosis-Related Cysteine Protease; Apoptotic Protease Activating Factor 3;
Entrez Gene ID
UniProt ID
Cat CBMAB-C5159-CQ
Conjugates
Size
Price $
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