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Mouse Anti-CCL16 Recombinant Antibody (CBFYC-0937) (CBMAB-C0993-FY)

This product is mouse antibody that recognizes CCL16. The antibody CBFYC-0937 can be used for immunoassay techniques such as: ELISA.
See all CCL16 antibodies

Summary

Host Animal
Mouse
Specificity
Human
Clone
CBFYC-0937
Antibody Isotype
IgG1
Application
ELISA

Basic Information

Immunogen
Recombinant Human CCL16HCC-4NCC4 Protein
Specificity
Human
Antibody Isotype
IgG1
Clonality
Monoclonal
Application Notes
The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Format
Liquid
Storage
Store at +4°C short term (1-2 weeks). Aliquot and store at-20°C long term. Avoid repeated freeze/thaw cycles.

Target

Full Name
C-C Motif Chemokine Ligand 16
Introduction
CCL16 (C-C Motif Chemokine Ligand 16) is a Protein Coding gene. Diseases associated with CCL16 include Corneal Dystrophy, Lisch Epithelial and Visceral Leishmaniasis. Among its related pathways are PEDF Induced Signaling and Akt Signaling. Gene Ontology (GO) annotations related to this gene include chemokine activity and chemoattractant activity. An important paralog of this gene is CCL14.
Entrez Gene ID
UniProt ID
Alternative Names
C-C Motif Chemokine Ligand 16; Small Inducible Cytokine Subfamily A (Cys-Cys), Member 16; Lymphocyte And Monocyte Chemoattractant; Chemokine (C-C Motif) Ligand 16; Small-Inducible Cytokine A16; Liver-Expressed Chemokine; IL-10-Inducible Chemokine; Chemokine LEC; Monotactin-1; SCYA16; ILINCK; Mtn-1; HCC-4
Function
Shows chemotactic activity for lymphocytes and monocytes but not neutrophils. Also shows potent myelosuppressive activity, suppresses proliferation of myeloid progenitor cells. Recombinant SCYA16 shows chemotactic activity for monocytes and THP-1 monocytes, but not for resting lymphocytes and neutrophils. Induces a calcium flux in THP-1 cells that were desensitized by prior expression to RANTES.
Biological Process
Cell-cell signaling Source: ProtInc
Cell communication Source: ProtInc
Cellular response to interferon-gamma Source: GO_Central
Cellular response to interleukin-1 Source: GO_Central
Cellular response to tumor necrosis factor Source: GO_Central
Chemokine-mediated signaling pathway Source: GO_Central
Chemotaxis Source: ProtInc
G protein-coupled receptor signaling pathway Source: GO_Central
Inflammatory response Source: GO_Central
Lymphocyte chemotaxis Source: GO_Central
Monocyte chemotaxis Source: GO_Central
Neutrophil chemotaxis Source: GO_Central
Positive regulation of ERK1 and ERK2 cascade Source: GO_Central
Positive regulation of GTPase activity Source: GO_Central
Cellular Location
Secreted
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For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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