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Rat Anti-CD209A Recombinant Antibody (CBFYC-1158) (CBMAB-C1216-FY)

This product is rat antibody that recognizes CD209A. The antibody CBFYC-1158 can be used for immunoassay techniques such as: IHC.
See all CD209A antibodies

Summary

Host Animal
Rat
Specificity
Mouse
Clone
CBFYC-1158
Antibody Isotype
IgG2a, k
Application
IHC

Basic Information

Immunogen
Recombinant protein corresponding to mouse DC-SIGN fused to His-tag (NP_573501)
Specificity
Mouse
Antibody Isotype
IgG2a, k
Clonality
Monoclonal
Application Notes
The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Format
Liquid
Storage
Store at +4°C short term (1-2 weeks). Aliquot and store at-20°C long term. Avoid repeated freeze/thaw cycles.

Target

Full Name
Cd209A Antigen
Introduction
CD209 (CD209 Molecule) is a Protein Coding gene. Diseases associated with CD209 include Dengue Virus and Human Immunodeficiency Virus Type 1. Among its related pathways are CLEC7A (Dectin-1) signaling and Hematopoietic Stem Cell Differentiation Pathways and Lineage-specific Markers. Gene Ontology (GO) annotations related to this gene include carbohydrate binding and mannose binding. An important paralog of this gene is CLEC4M.
Entrez Gene ID
UniProt ID
Alternative Names
CIRE; CD209; CDSIGN; Dcsign; SIGNR5; DC-SIGN; SIGN-R1; DC-SIGN1
Function
Probable pathogen-recognition receptor. May mediate the endocytosis of pathogens which are subsequently degraded in lysosomal compartments. May recognize in a calcium-dependent manner high mannose N-linked oligosaccharides in a variety of pathogen antigens.
Biological Process
Endocytosis Source: UniProtKB-KW
Regulation of T cell proliferation Source: MGI
Viral entry into host cell Source: MGI
Cellular Location
Membrane
Topology
Cytoplasmic: 1-51
Helical: 52-72
Extracellular: 73-238
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For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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