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Mouse Anti-CD68 Recombinant Antibody (CBYY-C1553) (CBMAB-C2991-YY)

This product is mouse antibody that recognizes CD68. The antibody CBYY-C1553 can be used for immunoassay techniques such as: FC
See all CD68 antibodies

Summary

Host Animal
Mouse
Specificity
Human
Clone
CBYY-C1553
Antibody Isotype
IgG2b
Application
FC

Basic Information

Immunogen
Human CD68/SR-D1
Specificity
Human
Antibody Isotype
IgG2b
Clonality
Monoclonal
Application Notes
The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Format
Purified Ig
Buffer
0.05 mg/mL
Preservative
PBS
Concentration
Liquid
Storage
Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.

Target

Full Name
CD68 Molecule
Entrez Gene ID
968
UniProt ID
P34810
Alternative Names
CD80 Molecule; CD80 Antigen (CD28 Antigen Ligand 1, B7-1 Antigen); B-Lymphocyte Activation Antigen B7; CTLA-4 Counter-Receptor B7.1; Activation B7-1 Antigen; CD28LG1; CD28LG; LAB7; BB1;
Function
Could play a role in phagocytic activities of tissue macrophages, both in intracellular lysosomal metabolism and extracellular cell-cell and cell-pathogen interactions. Binds to tissue- and organ-specific lectins or selectins, allowing homing of macrophage subsets to particular sites. Rapid recirculation of CD68 from endosomes and lysosomes to the plasma membrane may allow macrophages to crawl over selectin-bearing substrates or other cells.
Biological Process
Aging Source: ARUK-UCL
Autocrine signaling Source: Ensembl
Cellular response to lipopolysaccharide Source: ARUK-UCL
Cellular response to nutrient levels Source: ARUK-UCL
Cellular response to oxidised low-density lipoprotein particle stimulus Source: ARUK-UCL
Establishment of protein localization to organelle Source: GO_Central
Inflammatory response to antigenic stimulus Source: ARUK-UCL
Negative regulation of dendritic cell antigen processing and presentation Source: ARUK-UCL
Neutrophil degranulation Source: Reactome
Cellular Location
Isoform Short: Cell membrane
Isoform Long: Lysosome membrane; Endosome membrane
Topology
Extracellular: 22-319
Helical: 320-344
Cytoplasmic: 345-354
PTM
N- and O-glycosylated.
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For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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