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Mouse Anti-CEACAM5 (AA 35-680) Recombinant Antibody (CBYY-C1849) (CBMAB-C3287-YY)

This product is mouse antibody that recognizes CEACAM5 . The antibody CBYY-C1849 can be used for immunoassay techniques such as: IHC-P, WB
See all CEACAM5 antibodies

Summary

Host Animal
Mouse
Specificity
Human
Clone
CBYY-C1849
Antibody Isotype
IgG1
Application
IHC-P, WB

Basic Information

Specificity
Human
Antibody Isotype
IgG1
Clonality
Monoclonal
Application Notes
The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Format
Immunoaffinity purified
Buffer
1 mg/mL
Preservative
50% glycerol, 1% BSA, PBS, pH 7.3
Concentration
Liquid
Storage
Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.
Epitope
AA 35-680

Target

Full Name
Carcinoembryonic Antigen Related Cell Adhesion Molecule 5
Entrez Gene ID
1048
UniProt ID
P06731
Alternative Names
Centrosomal Protein 55; Up-Regulated In Colon Cancer 6; Cancer/Testis Antigen 111; Centrosomal Protein 55kDa; C10orf3; URCC6;
Function
Cell surface glycoprotein that plays a role in cell adhesion, intracellular signaling and tumor progression (PubMed:2803308, PubMed:10910050, PubMed:10864933).
Mediates homophilic and heterophilic cell adhesion with other carcinoembryonic antigen-related cell adhesion molecules, such as CEACAM6 (PubMed:2803308).
Plays a role as an oncogene by promoting tumor progression; induces resistance to anoikis of colorectal carcinoma cells (PubMed:10910050).
(Microbial infection) Receptor for E.coli Dr adhesins. Binding of E.coli Dr adhesins leads to dissociation of the homodimer.
Biological Process
Apoptotic process Source: UniProtKB-KW
Heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules Source: UniProtKB
Homophilic cell adhesion via plasma membrane adhesion molecules Source: UniProtKB
Homotypic cell-cell adhesion Source: UniProtKB
Leukocyte migration Source: Reactome
Negative regulation of anoikis Source: UniProtKB
Negative regulation of apoptotic process Source: UniProtKB
Negative regulation of myotube differentiation Source: UniProtKB
Cellular Location
Cell membrane; Apical cell membrane; Cell surface. Localized to the apical glycocalyx surface.
PTM
Complex immunoreactive glycoprotein with a MW of 180 kDa comprising 60% carbohydrate.
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For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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