Mouse Anti-CHAD Recombinant Antibody (CBYY-C3239) (CBMAB-C4682-YY)

This product is mouse antibody that recognizes CHAD. The antibody CBYY-C3239 can be used for immunoassay techniques such as: ELISA
See all CHAD antibodies

Datasheet

Summary

Host Animal

Mouse

Specificity

Human

Clone

CBYY-C3239

Antibody Isotype

IgG2a, κ

Application

ELISA

Basic Information

Specificity

Human

Antibody Isotype

IgG2a, κ

Clonality

Monoclonal

Application Notes

The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Format

Protein A purified

Preservative

PBS, pH 7.2

Concentration

Liquid

Storage

Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.

Target

Full Name

chondroadherin

Entrez Gene ID

1101

UniProt ID

O15335

Alternative Names

Chromogranin A; Parathyroid Secretory Protein 1; Pituitary Secretory Protein I; SP-I; CGA; Betagranin (N-Terminal Fragment Of Chromogranin A); Chromogranin-A;

Function

Promotes attachment of chondrocytes, fibroblasts, and osteoblasts. This binding is mediated (at least for chondrocytes and fibroblasts) by the integrin alpha2beta1. May play an important role in the regulation of chondrocyte growth and proliferation (By similarity).

Biological Process

Bone development Source: Ensembl
Negative regulation of bone trabecula formation Source: Ensembl

Cellular Location

Extracellular matrix

References

Karaarslan, N., Yilmaz, I., Sirin, D. Y., Ozbek, H., Kaya, Y. E., Akyuva, Y., ... & Erdem, I. (2018). Does transcription factor, induced by daptomycin and vancomycin, affect HIF-1α, Chondroadherin, and COL2A1?. Annals of Medical Research, 25(4), 756-762.

Sirin, D. Y., Kaplan, N., Yilmaz, I., Karaarslan, N., Ozbek, H., Akyuva, Y., ... & Mahirogullari, M. (2018). The association between different molecular weights of hyaluronic acid and CHAD, HIF-1α, COL2A1 expression in chondrocyte cultures. Experimental and therapeutic medicine, 15(5), 4205-4212.

Rämisch, S., Pramhed, A., Tillgren, V., Aspberg, A., & Logan, D. T. (2017). Crystal structure of human chondroadherin: solving a difficult molecular-replacement problem using de novo models. Acta Crystallographica Section D: Structural Biology, 73(1), 53-63.

Deng, X., Wei, W., Huang, N., Shi, Y., Huang, M., Yan, Y., ... & Wang, X. (2017). Tumor repressor gene chondroadherin oppose migration and proliferation in hepatocellular carcinoma and predicts a good survival. Oncotarget, 8(36), 60270.

Paracuellos, P., Kalamajski, S., Bonna, A., Bihan, D., Farndale, R. W., & Hohenester, E. (2017). Structural and functional analysis of two small leucine-rich repeat proteoglycans, fibromodulin and chondroadherin. Matrix Biology, 63, 106-116.

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Protocols

Please try the standard protocols which include: protocols, troubleshooting and guide.

Enzyme-linked Immunosorbent Assay (ELISA)
Flow Cytometry
Immunofluorescence (IF)
Immunohistochemistry (IHC)
Immunoprecipitation (IP)
Western Blot (WB)
Enzyme Linked Immunospot (ELISpot)
Proteogenomic
Other Protocols

Associated Products

Related Products

Mouse Anti-CHAD Recombinant Antibody (8B7)

Isotype control

For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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