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Mouse Anti-CHST10 Recombinant Antibody (1C10) (CBMAB-0065-CN)

This product is a mouse antibody that recognizes CHST10 of chicken. The antibody 1C10 can be used for immunoassay techniques such as: IHC.
See all CHST10 antibodies

Summary

Host Animal
Mouse
Specificity
Chicken, Human
Clone
1C10
Antibody Isotype
IgG1
Application
IHC

Basic Information

Immunogen
Chicken optic nerve
Specificity
Chicken, Human
Antibody Isotype
IgG1
Clonality
Monoclonal
Application Notes
The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Format
Liquid
Purity
>95%, as determined by SDS-PAGE analysis
Storage
Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.

Target

Full Name
Carbohydrate Sulfotransferase 10
Introduction
This protein encoded by this gene catalyzes the transfer of sulfate to position 3 of terminal glucuronic acid of both protein- and lipid-linked oligosaccharides. This protein was first identified as a sulfotransferase that acts on the human natural killer-1 (HNK-1) glycan; HNK-1 is a carbohydrate involved in neurodevelopment and synaptic plasticity.
Entrez Gene ID
Human9486
Chicken395206
UniProt ID
HumanO43529
ChickenQ5ZIE4
Alternative Names
HNK-1 sulfotransferase; HNK-1ST; HNK1ST
Function
Catalyzes the transfer of sulfate to position 3 of terminal glucuronic acid of both protein- and lipid-linked oligosaccharides. Participates in biosynthesis of HNK-1 carbohydrate structure, a sulfated glucuronyl-lactosaminyl residue carried by many neural recognition molecules, which is involved in cell interactions during ontogenetic development and in synaptic plasticity in the adult. May be indirectly involved in synapse plasticity of the hippocampus, via its role in HNK-1 biosynthesis.
Biological Process
Carbohydrate biosynthetic process Source: InterPro
Cell adhesion Source: ProtInc
Proteoglycan biosynthetic process Source: GO_Central
Cellular Location
Golgi apparatus membrane
Topology
Cytoplasmic: 1-6
Helical: 7-27
Lumenal: 28-356
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For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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