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Rat Anti-CLEC10A Recombinant Antibody (CBWJC-2779) (CBMAB-C3892WJ)

This product is a Rat antibody that recognizes CLEC10A. This antibody CBWJC-2779 can be used for immunoassay techniques such as: FC, IHC, IP.
See all CLEC10A antibodies

Summary

Host Animal
Rat
Specificity
Mouse
Clone
CBWJC-2779
Antibody Isotype
IgG2a, κ
Application
FC, IHC, IP

Basic Information

Immunogen
Purified and recombinant mouse MGL1
Specificity
Mouse
Antibody Isotype
IgG2a, κ
Application Notes
The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Format
Liquid
Buffer
PBS, pH 7.2,
Preservative
0.09% sodium azide
Concentration
0.5 mg/mL
Storage
Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.

Target

Full Name
C-type lectin domain family 10, member A
Introduction
This gene encodes a member of the C-type lectin/C-type lectin-like domain (CTL/CTLD) superfamily. Members of this family share a common protein fold and have diverse functions, such as cell adhesion, cell-cell signalling, glycoprotein turnover, and roles in inflammation and immune response. The encoded type 2 transmembrane protein may function as a cell surface antigen. Two transcript variants encoding distinct isoforms have been identified for this gene. [provided by RefSeq, Jul 2008]
Entrez Gene ID
17312
UniProt ID
P49300
Alternative Names
C-Type Lectin Domain Containing 10A; C-Type (Calcium Dependent, Carbohydrate-Recognition Domain) Lectin, Superfamily Member 14 (Macrophage-Derived); Macrophage Lectin 2 (Calcium Dependent); C-Type Lectin Domain Family 10 Member A; CLECSF13; CLECSF14; HML; C-Type (Calcium Dependent, Carbohydrate-Recognition Domain) Lectin, Superfamily Member 13 (Macrophage-Derived);
Function
Probable role in regulating adaptive and innate immune responses. Binds in a calcium-dependent manner to terminal galactose and N-acetylgalactosamine units, linked to serine or threonine. These sugar moieties are known as Tn-Ag and are expressed in a variety of carcinoma cells.
Biological Process
Adaptive immune response Source: UniProtKB-KW
Endocytosis Source: UniProtKB-KW
Innate immune response Source: UniProtKB-KW
Stimulatory C-type lectin receptor signaling pathway Source: Reactome
Cellular Location
Membrane
Topology
Cytoplasmic: 1-39
Helical: 40-60
Extracellular: 61-316
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For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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