Recombinant protein corresponding to aa1-245 from human CMBL expressed in E. coli
Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freezethaw cycles.
CMBL (EC 220.127.116.11) is a cysteine hydrolase of the dienelactone hydrolase family that is highly expressed in liver cytosol. CMBL preferentially cleaves cyclic esters, and it activates medoxomil-ester prodrugs in which the medoxomil moiety is linked to an oxygen atom (Ishizuka et al., 2010 [PubMed 20177059]).[supplied by OMIM, Apr 2010]
Carboxymethylenebutenolidase Homolog; Carboxymethylenebutenolidase Homolog (Pseudomonas); Carboxymethylenebutenolidase-Like (Pseudomonas); EC 3.1.-.-; JS-1;