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Mouse Anti-CMBL (AA 1-245) Recombinant Antibody (CBFYC-0520) (CBMAB-C0571-FY)

This product is mouse antibody that recognizes CMBL. The antibody CBFYC-0520 can be used for immunoassay techniques such as: WB, ELISA.
See all CMBL antibodies

Summary

Host Animal
Mouse
Specificity
Human
Clone
CBFYC-0520
Antibody Isotype
IgG2a, k
Application
WB, ELISA

Basic Information

Immunogen
Recombinant human CMBL (1-245aa) purified from E. coli
Specificity
Human
Antibody Isotype
IgG2a, k
Clonality
Monoclonal
Application Notes
The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Format
Liquid
Concentration
1 mg/mL
Storage
Store at +4°C short term (1-2 weeks). Aliquot and store at-20°C long term. Avoid repeated freeze/thaw cycles.
Epitope
AA 1-245

Target

Full Name
Carboxymethylenebutenolidase Homolog
Introduction
CMBL is a cysteine hydrolase of the dienelactone hydrolase family that is highly expressed in liver cytosol. CMBL preferentially cleaves cyclic esters, and it activates medoxomil-ester prodrugs in which the medoxomil moiety is linked to an oxygen atom.
Entrez Gene ID
UniProt ID
Alternative Names
Carboxymethylenebutenolidase Homolog; Carboxymethylenebutenolidase Homolog (Pseudomonas); Carboxymethylenebutenolidase-Like (Pseudomonas); EC 3.1.-.-; JS-1
Function
Cysteine hydrolase. Can convert the prodrug olmesartan medoxomil into its pharmacologically active metabolite olmerstatan, an angiotensin receptor blocker, in liver and intestine. May also activate beta-lactam antibiotics faropenem medoxomil and lenampicillin.
Biological Process
Xenobiotic metabolic process Source: Reactome
Cellular Location
Cytosol
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For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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