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Mouse Anti-COA7 Recombinant Antibody (CBLC168-LY) (CBMAB-C11088-LY)

The product is antibody recognizes COA7. The antibody CBLC168-LY immunoassay techniques such as: WB.
See all COA7 antibodies

Summary

Host Animal
Mouse
Specificity
Human
Clone
CBLC168-LY
Antibody Isotype
IgG1
Application
WB

Basic Information

Specificity
Human
Antibody Isotype
IgG1
Clonality
Monoclonal
Application Notes
The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Format
Liquid
Concentration
1 mg/mL
Purity
> 95% Purity determined by SDS-PAGE.
Storage
Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freezethaw cycles.

Target

Full Name
Cytochrome C Oxidase Assembly Factor 7 (Putative)
Introduction
COA7 (Cytochrome C Oxidase Assembly Factor 7 (Putative)) is a Protein Coding gene. Diseases associated with COA7 include Mitochondrial Complex Iv Deficiency.
Entrez Gene ID
65260
UniProt ID
Q96BR5
Alternative Names
Cytochrome C Oxidase Assembly Factor 7 (Putative); Cytochrome C Oxidase Assembly Factor 7; Respiratory Chain Assembly Factor 1; Sel1 Repeat-Containing Protein 1; Beta-Lactamase Hcp-Like Protein; Respiratory Chain Assembly 1; Sel1 Repeat Containing 1;
Function
Required for assembly of mitochondrial respiratory chain complex I and complex IV.
Cellular Location
Mitochondrion intermembrane space. The import in the mitochondrion intermembrane space is mediated by CHCHD4/MIA40.
Involvement in disease
Spinocerebellar ataxia, autosomal recessive, with axonal neuropathy 3 (SCAN3):
A form of spinocerebellar ataxia, a clinically and genetically heterogeneous group of cerebellar disorders due to degeneration of the cerebellum with variable involvement of the brainstem and spinal cord. SCAN3 is an autosomal recessive disorder characterized by onset in the first decade of slowly progressive distal muscle weakness and atrophy and distal sensory impairment due to an axonal peripheral neuropathy. Affected individuals have gait disturbances and sometimes manual dexterity difficulties, as well as cerebellar ataxia associated with cerebellar atrophy on brain imaging.
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For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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