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Mouse Anti-COIL Recombinant Antibody (IH10) (CBMAB-0249CQ)

This product is a mouse antibody that recognizes COIL. The antibody IH10 can be used for immunoassay techniques such as: FC, IF, IHC-P, IP, WB.
See all COIL antibodies

Summary

Host Animal
Mouse
Specificity
Human
Clone
IH10
Antibody Isotype
IgG2b
Application
FC, IF, IHC-P, IP, WB

Basic Information

Immunogen
Synthetic peptide of Human Coilin
Specificity
Human
Antibody Isotype
IgG2b
Clonality
Monoclonal
Application Notes
The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Purity
>95% as determined by analysis by SDS-PAGE
Storage
Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.

Target

Full Name
Coilin
Introduction
The protein encoded by this gene is an integral component of Cajal bodies (also called coiled bodies). Component of nuclear coiled bodies, also known as Cajal bodies or CBs, which are involved in the modification and assembly of nucleoplasmic snRNPs.
Entrez Gene ID
8161
UniProt ID
P38432
Alternative Names
Coilin; P80-Coilin; CLN80; Coilin P80; P80
Function
Component of nuclear coiled bodies, also known as Cajal bodies or CBs, which are involved in the modification and assembly of nucleoplasmic snRNPs.
Biological Process
Spliceosomal snRNP assembly Source: GO_Central
Cellular Location
Nucleus; Cajal body
PTM
Symmetrical dimethylation of arginine residues within the RG repeat region enhances affinity for SMN, and thus localization of SMN complexes to CBs.
Phosphorylation during mitosis is associated with disassembly of CBs.
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For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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