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Mouse Anti-CRIPT Recombinant Antibody (CBCNC-356) (CBMAB-C2829-CN)

This product is a Mouse antibody that recognizes CRIPT. The antibody CBCNC-356 can be used for immunoassay techniques such as: ELISA, ELISA-capture, WB.
See all CRIPT antibodies

Summary

Host Animal
Mouse
Specificity
Human
Clone
CBCNC-356
Antibody Isotype
IgG2a, κ
Application
ELISA, ELISA-capture, WB

Basic Information

Specificity
Human
Antibody Isotype
IgG2a, κ
Clonality
Monoclonal
Application Notes
The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Target

Full Name
cysteine-rich PDZ-binding protein
Introduction
CRIPT (CXXC Repeat Containing Interactor Of PDZ3 Domain) is a Protein Coding gene. Diseases associated with CRIPT include Short Stature With Microcephaly And Distinctive Facies and Isolated Growth Hormone Deficiency, Type Ia. Gene Ontology (GO) annotations related to this gene include protein complex binding and PDZ domain binding.
Entrez Gene ID
9419
UniProt ID
Q9P021
Alternative Names
CXXC Repeat Containing Interactor Of PDZ3 Domain; Cysteine-Rich Interactor Of PDZ Three; Cysteine-Rich PDZ-Binding Protein; Cysteine-Rich Interactor Of PDZ3; Postsynaptic Protein CRIPT; HSPC139; SSMDF;
Function
Involved in the cytoskeletal anchoring of DLG4 in excitatory synapses.
Biological Process
Cytoplasmic microtubule organization Source: UniProtKB
Establishment of protein localization Source: UniProtKB
Protein localization to microtubule Source: UniProtKB
Regulation of postsynaptic density protein 95 clustering Source: UniProtKB
Cellular Location
Cytoplasm; Synapse; Dendritic spine. Colocalizes with DLG4 in asymmetric synapses.
Involvement in disease
Short stature with microcephaly and distinctive facies (SSMCF):
An autosomal recessive disease characterized by dwarfism, microcephaly, and distinctive facial dysmorphism involving frontal bossing, high forehead, sparse hair and eyebrows, telecanthus, mild proptosis, anteverted nares, and flat nasal bridge.
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For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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