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Mouse Anti-CRIPT Recombinant Antibody (CBLNC-194) (CBMAB-1440-CN)

This product is a mouse antibody that recognizes CRIPT of human. The antibody CBLNC-194 can be used for immunoassay techniques such as: WB, ELISA.
See all CRIPT antibodies

Summary

Host Animal
Mouse
Specificity
Human
Clone
CBLNC-194
Antibody Isotype
IgG2a
Application
WB, ELISA

Basic Information

Specificity
Human
Antibody Isotype
IgG2a
Clonality
Monoclonal
Application Notes
The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Format
Liquid
Storage
Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.

Target

Full Name
cysteine-rich PDZ-binding protein
Introduction
This gene encodes a protein that binds to the PDZ3 peptide recognition domain. The protein may modulates protein interactions with the cytoskeleton. A mutation in this gene resulted in short stature with microcephaly and distinctive facies. Involved in the cytoskeletal anchoring of DLG4 in excitatory synapses.
Entrez Gene ID
9419
UniProt ID
Q9P021
Alternative Names
SSMDF; HSPC139
Function
Involved in the cytoskeletal anchoring of DLG4 in excitatory synapses.
Biological Process
Cytoplasmic microtubule organization Source: UniProtKB
Establishment of protein localization Source: UniProtKB
Protein localization to microtubule Source: UniProtKB
Regulation of postsynaptic density protein 95 clustering Source: UniProtKB
Cellular Location
Cytoplasm; Synapse; Dendritic spine. Colocalizes with DLG4 in asymmetric synapses.
Involvement in disease
Short stature with microcephaly and distinctive facies (SSMCF):
An autosomal recessive disease characterized by dwarfism, microcephaly, and distinctive facial dysmorphism involving frontal bossing, high forehead, sparse hair and eyebrows, telecanthus, mild proptosis, anteverted nares, and flat nasal bridge.
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For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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