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Mouse Anti-CRISP1 Recombinant Antibody (CBWJC-3083) (CBMAB-C4253WJ)

This product is a Mouse antibody that recognizes CRISP1. This antibody CBWJC-3083 can be used for immunoassay techniques such as: IHC.
See all CRISP1 antibodies

Summary

Host Animal
Mouse
Specificity
Human
Clone
CBWJC-3083
Antibody Isotype
IgM
Application
IHC

Basic Information

Immunogen
Prepared from lymphocytes and SU-DHL4 cell line
Specificity
Human
Antibody Isotype
IgM
Application Notes
The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Format
Liquid
Storage
Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.

Target

Full Name
Cysteine Rich Secretory Protein 1
Introduction
CRISP1 (Cysteine Rich Secretory Protein 1) is a Protein Coding gene. Gene Ontology (GO) annotations related to this gene include calcium channel regulator activity. An important paralog of this gene is CRISP2.
Entrez Gene ID
167
UniProt ID
P54107
Alternative Names
Cysteine Rich Secretory Protein 1; Acidic Epididymal Glycoprotein Homolog; Acidic Epididymal Glycoprotein-Like 1; AEG-Like Protein; CRISP-1; AEGL1; ARP; Cysteine-Rich Secretory Protein-1 Delta;
Function
May have a role in sperm-egg fusion and maturation.
Biological Process
Binding of sperm to zona pellucida Source: GO_Central
Fusion of sperm to egg plasma membrane involved in single fertilization Source: ProtInc

Kumar, S., Leeb, A. S., Vaughan, A. M., & Kappe, S. H. (2022). A Plasmodium falciparum Cysteine Rich Secretory protein uniquely localizes to one end of male gametes. Molecular and Biochemical Parasitology, 111447.

Jorasia, K., Paul, R. K., Rathore, N. S., Lal, P., Singh, R., & Sareen, M. (2021). Production of bioactive recombinant ovine cysteine-rich secretory protein 1 in Escherichia coli. Systems biology in reproductive medicine, 67(6), 471-481.

Arévalo, L., Brukman, N. G., Cuasnicú, P. S., & Roldan, E. R. (2020). Evolutionary analysis of genes coding for Cysteine-RIch Secretory Proteins (CRISPs) in mammals. BMC evolutionary biology, 20(1), 1-13.

Bernardes, C. P., Menaldo, D. L., Zoccal, K. F., Boldrini-Franca, J., Peigneur, S., Arantes, E. C., ... & Sampaio, S. V. (2019). First report on BaltCRP, a cysteine-rich secretory protein (CRISP) from Bothrops alternatus venom: effects on potassium channels and inflammatory processes. International journal of biological macromolecules, 140, 556-567.

Weigel Muñoz, M., Battistone, M. A., Carvajal, G., Maldera, J. A., Curci, L., Torres, P., ... & Cuasnicú, P. S. (2018). Influence of the genetic background on the reproductive phenotype of mice lacking Cysteine-Rich Secretory Protein 1 (CRISP1). Biology of Reproduction, 99(2), 373-383.

Lodovicho, M. E., Costa, T. R., Bernardes, C. P., Menaldo, D. L., Zoccal, K. F., Carone, S. E., ... & Sampaio, S. V. (2017). Investigating possible biological targets of Bj-CRP, the first cysteine-rich secretory protein (CRISP) isolated from Bothrops jararaca snake venom. Toxicology letters, 265, 156-169.

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For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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