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Mouse Anti-CRYBB3 Recombinant Antibody (4H6) (CBMAB-C7067-LY)

This product is antibody recognizes CRYBB3. The antibody 4H6 immunoassay techniques such as: WB.
See all CRYBB3 antibodies

Summary

Host Animal
Mouse
Specificity
Human
Clone
4H6
Antibody Isotype
IgG2a, κ
Application
WB

Basic Information

Immunogen
CRYBB3 (NP_004067.1, 112 a.a. ~ 211 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa
Specificity
Human
Antibody Isotype
IgG2a, κ
Clonality
Monoclonal
Application Notes
The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Format
Liquid
Storage
Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freezethaw cycles.

Target

Full Name
crystallin, beta B3
Introduction
CRYBB3 (Crystallin Beta B3) is a Protein Coding gene. Diseases associated with CRYBB3 include Cataract 22, Multiple Types and Cataract 24. Gene Ontology (GO) annotations related to this gene include structural constituent of eye lens. An important paralog of this gene is CRYBB2.
Entrez Gene ID
1417
UniProt ID
P26998
Alternative Names
Crystallin Beta B3; CRYB3; Eye Lens Structural Protein; Crystallin, Beta B3; Beta-Crystallin B3; Beta-B3 Crystallin; CTRCT22; CATCN2;
Function
Crystallins are the dominant structural components of the vertebrate eye lens.
Biological Process
Lens development in camera-type eye Source: GO_Central
Visual perception Source: GO_Central
Involvement in disease
Cataract 22, multiple types (CTRCT22):
An opacification of the crystalline lens of the eye that frequently results in visual impairment or blindness. Opacities vary in morphology, are often confined to a portion of the lens, and may be static or progressive. In general, the more posteriorly located and dense an opacity, the greater the impact on visual function. CTRCT22 includes nuclear cataract among others. Nuclear cataracts affect the central nucleus of the eye, and are often not highly visually significant. The density of the opacities varies greatly from fine dots to a dense, white and chalk-like, central cataract. The condition is usually bilateral. Nuclear cataracts are often combined with opacified cortical fibers encircling the nuclear opacity, which are referred to as cortical riders.
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For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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