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Mouse Anti-CSF3 Recombinant Antibody (CBWJC-3194) (CBMAB-C4383WJ)

This product is a Mouse antibody that recognizes CSF3. This antibody CBWJC-3194 can be used for immunoassay techniques such as: WB.
See all CSF3 antibodies

Summary

Host Animal
Mouse
Specificity
Human
Clone
CBWJC-3194
Antibody Isotype
IgG1
Application
WB

Basic Information

Immunogen
Human recombinant protein fragment corresponding to aa30-207 of human CSF3 (NP_000750) produced in E.coli
Specificity
Human
Antibody Isotype
IgG1
Clonality
Monoclonal
Application Notes
The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Format
Liquid
Buffer
PBS (PH 7.3), 1% BSA, 50% glycerol
Preservative
0.02% sodium azide
Concentration
1 mg/mL
Storage
Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.

Target

Full Name
Colony Stimulating Factor 3
Introduction
CSF3 (Colony Stimulating Factor 3) is a Protein Coding gene. Diseases associated with CSF3 include Neutropenia and Severe Congenital Neutropenia. Among its related pathways are PEDF Induced Signaling and Cytokine Signaling in Immune system. Gene Ontology (GO) annotations related to this gene include enzyme binding and growth factor activity.
Entrez Gene ID
UniProt ID
Alternative Names
Colony Stimulating Factor 3; Pluripoietin; Lenograstim; Filgrastim; Colony Stimulating Factor 3 (Granulocyte); C17orf33; GCSF;
Function
Granulocyte/macrophage colony-stimulating factors are cytokines that act in hematopoiesis by controlling the production, differentiation, and function of 2 related white cell populations of the blood, the granulocytes and the monocytes-macrophages. This CSF induces granulocytes.
Biological Process
Cellular response to cytokine stimulus Source: BHF-UCL
Cellular response to lipopolysaccharide Source: Ensembl
Cytokine-mediated signaling pathway Source: Reactome
Granulocyte differentiation Source: UniProtKB
Immune response Source: InterPro
Multicellular organism development Source: ProtInc
Negative regulation of neuron death Source: Ensembl
Positive regulation of actin cytoskeleton reorganization Source: BHF-UCL
Positive regulation of actin filament polymerization Source: BHF-UCL
Positive regulation of cell population proliferation Source: GO_Central
Positive regulation of DNA-binding transcription factor activity Source: BHF-UCL
Positive regulation of myeloid cell differentiation Source: GO_Central
Positive regulation of peptidyl-serine phosphorylation Source: BHF-UCL
Positive regulation of peptidyl-tyrosine phosphorylation Source: BHF-UCL
Positive regulation of phosphatidylinositol 3-kinase signaling Source: BHF-UCL
Positive regulation of protein binding Source: BHF-UCL
Positive regulation of protein kinase B signaling Source: BHF-UCL
Positive regulation of transcription by RNA polymerase II Source: BHF-UCL
Response to ethanol Source: Ensembl
Cellular Location
Secreted
PTM
O-glycan consists of Gal-GalNAc disaccharide which can be modified with up to two sialic acid residues (done in recombinantly expressed G-CSF from CHO cells).
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For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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