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Mouse Anti-CTXA Recombinant Antibody (241-438-1) (CBMAB-0109-CN)

This product is a mouse antibody that recognizes CTXA of Dictyostelium discoideum. The antibody 241-438-1 can be used for immunoassay techniques such as: BL, IHC, WB.
See all CTXA antibodies

Summary

Host Animal
Mouse
Specificity
D. discoideum, Dictyostelium
Clone
241-438-1
Antibody Isotype
IgG2b
Application
Blocking, IHC, WB

Basic Information

Immunogen
Cortexillin I
Specificity
D. discoideum, Dictyostelium
Antibody Isotype
IgG2b
Clonality
Monoclonal
Application Notes
The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Format
Liquid
Purity
>95%, as determined by SDS-PAGE analysis
Storage
Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.

Target

Full Name
Actin binding protein
Introduction
Member of the alpha-actinin/spectrin superfamily, dimerizes with cortexillin II; involved in cytokinesis and development and associates with the actin cytoskeleton.
Entrez Gene ID
8627162
UniProt ID
Q54HG2
Alternative Names
cortexillin I
Function
Actin-bundling protein. When linked to F-actin the actin filaments form preferentially anti-parallel bundles that associate into meshworks. Plays a major role in cytokinesis. Negatively regulates cortical localization of rapgap1.
Biological Process
Actin filament bundle assembly Source: dictyBase
Actin filament network formation Source: dictyBase
Actomyosin contractile ring contraction Source: dictyBase
Aggregation involved in sorocarp development Source: dictyBase
Bleb assembly Source: dictyBase
Cellular protein localization Source: dictyBase
Chemotaxis to cAMP Source: dictyBase
Cleavage furrow formation Source: dictyBase
Cortical actin cytoskeleton organization Source: dictyBase
Detection of mechanical stimulus Source: dictyBase
Epithelial cell morphogenesis Source: dictyBase
Establishment of protein localization Source: dictyBase
Mitotic cytokinesis Source: dictyBase
Positive regulation of cytoskeleton organization Source: dictyBase
Positive regulation of gene expression Source: dictyBase
Positive regulation of protein phosphorylation Source: dictyBase
Protein localization to cleavage furrow Source: dictyBase
Regulation of GTPase activity Source: dictyBase
Regulation of myosin II filament assembly Source: dictyBase
Response to bacterium Source: dictyBase
Sexual reproduction Source: dictyBase
Sorocarp stalk morphogenesis Source: dictyBase
Cellular Location
Cytoskeleton
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For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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