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Mouse Anti-CX3CR1 Recombinant Antibody (8E10.D9) (CBMAB-1500-CN)

This product is a mouse antibody that recognizes CX3CR1 of human. The antibody 8E10.D9 can be used for immunoassay techniques such as: IHC-Fr, IHC-P, WB.
Host Species
Mouse
Application
IHC-Fr, IHC-P, WB
Immunogen
Synthetic peptide corresponding to Human CX3CR1 aa. 207-222 conjugated to Keyhole Limpet Haemocyanin (KLH).
Sequence: MSYCYFRIIQTLFSCK
Antibody Isotype
IgG1
Specificity
Human
Clone
8E10.D9
Format
Liquid
Storage
Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.
Introduction
Fractalkine is a transmembrane protein and chemokine involved in the adhesion and migration of leukocytes. The protein encoded by this gene is a receptor for fractalkine. The encoded protein also is a coreceptor for HIV-1, and some variations in this gene lead to increased susceptibility to HIV-1 infection and rapid progression to AIDS. This protein acts as coreceptor with CD4 for HIV-1 virus envelope protein (in vitro) (PubMed:9726990). Isoform 2 and isoform 3 seem to be more potent HIV-1 coreceptors than isoform 1.
Alternative Name
V28; CCRL1; GPR13; CMKDR1; GPRV28; CMKBRL1
Entrez Gene ID
UniProt ID
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For Research Use Only. Not For Clinical Use.
Cat CBMAB-1500-CN
Conjugates
Size
Price $
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Second antibody and isotype control