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Mouse Anti-CXXC1 Recombinant Antibody (CBLNC-153) (CBMAB-1508-CN)

This product is a mouse antibody that recognizes CXXC1 of human. The antibody CBLNC-153 can be used for immunoassay techniques such as: WB, ELISA, RIA.
See all CXXC1 antibodies

Summary

Host Animal
Mouse
Specificity
Human
Clone
CBLNC-153
Antibody Isotype
IgG1
Application
WB, ELISA, RIA

Basic Information

Immunogen
BETA 7 EPITOPE of CGB /hCG Beta
Specificity
Human
Antibody Isotype
IgG1
Clonality
Monoclonal
Application Notes
The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Format
Liquid
Buffer
PBS, pH 7.4
Preservative
0.09% Sodium azide
Concentration
Lot specific
Storage
Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.
Epitope
Located in Chain beta 7

Target

Full Name
CXXC1
Introduction
Proteins that contain a CXXC motif within their DNA-binding domain, such as CXXC1, recognize CpG sequences and regulate gene expression. CXXC1 (CXXC finger protein 1) is a transcriptional activator that binds specifically to non-methylated CpG motifs through its CXXC domain. CXXC1 is a component of the SETD1 complex, regulates gene expression and is essential for vertebrate development.
Entrez Gene ID
UniProt ID
Alternative Names
CFP1; CGBP; SPP1; PCCX1; PHF18; hCGBP; ZCGPC1; HsT2645; 2410002I16Rik; 5830420C16Rik
Function
Transcriptional activator that exhibits a unique DNA binding specificity for CpG unmethylated motifs with a preference for CpGG.
Biological Process
Histone H3-K4 methylation Source: UniProtKB
IRE1-mediated unfolded protein response Source: Reactome
Positive regulation of transcription, DNA-templated Source: UniProtKB
Regulation of transcription, DNA-templated Source: UniProtKB
Cellular Location
Nucleus speckle; Nucleus. Associated with euchromatin. During mitosis, excluded from condensed chromosomes.
PTM
May be regulated by proteolysis.
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For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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