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Mouse Anti-CYB5R2 Recombinant Antibody (CBXC-2220) (CBMAB-C5441-CQ)

This product is a mouse antibody that recognizes CYB5R2. The antibody CBXC-2220 can be used for immunoassay techniques such as: WB, FC.
See all CYB5R2 antibodies

Summary

Host Animal
Mouse
Specificity
Human
Clone
CBXC-2220
Antibody Isotype
IgG2a
Application
WB, FC

Basic Information

Immunogen
Full length human recombinant protein of human CYB5R2 (NP_057313)
Specificity
Human
Antibody Isotype
IgG2a
Clonality
Monoclonal
Application Notes
The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Format
Liquid
Buffer
PBS, pH 7.3, 1% BSA, 50% glycerol
Preservative
0.02% sodium azide
Concentration
1.1 mg/mL
Storage
Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.

Target

Full Name
Cytochrome B5 Reductase 2
Introduction
CYB5R2 (Cytochrome B5 Reductase 2) is a Protein Coding gene. Among its related pathways are Metabolism and Amino sugar and nucleotide sugar metabolism. Gene Ontology (GO) annotations related to this gene include oxidoreductase activity and cytochrome-b5 reductase activity, acting on NAD(P)H. An important paralog of this gene is CYB5R3.
Entrez Gene ID
UniProt ID
Alternative Names
Cytochrome B5 Reductase 2; EC 1.6.2.2; B5R.2; NADH-Cytochrome B5 Reductase 2; Cytochrome B5 Reductase B5R.2;
Function
NADH-cytochrome b5 reductases are involved in desaturation and elongation of fatty acids, cholesterol biosynthesis, drug metabolism, and, in erythrocyte, methemoglobin reduction (By similarity).

Responsible for NADH-dependent lucigenin chemiluminescence in spermatozoa by reducing both lucigenin and 2-[4-iodophenyl]-3-[4-nitrophenyl]-5-[2,4-disulfophenyl]-2H tetrazolium monosodium salt (WST-1).
Biological Process
Bicarbonate transport Source: Reactome
Sterol biosynthetic process Source: UniProtKB-KW
Cellular Location
Endoplasmic reticulum membrane; Nucleus; Membrane
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For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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