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Mouse Anti-DAZAP2 Recombinant Antibody (3G21) (CBMAB-D0276-YC)

Provided herein is a Mouse monoclonal antibody, which binds to DAZ Associated Protein 2 (DAZAP2). The antibody can be used for immunoassay techniques, such as ELISA, WB.
See all DAZAP2 antibodies

Summary

Host Animal
Mouse
Specificity
Human
Clone
3G21
Antibody Isotype
IgG2b, κ
Application
ELISA, WB

Basic Information

Immunogen
DAZAP2 (NP_055579, 93 a.a. ~ 169 a.a) partial recombinant protein with GST tag
Specificity
Human
Antibody Isotype
IgG2b, κ
Application Notes
The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Storage
Store at 4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.

Target

Full Name
DAZ associated protein 2
Introduction
DAZAP2 is a proline-rich protein which interacts with the deleted in azoospermia (DAZ) and the deleted in azoospermia-like gene through the DAZ-like repeats. This protein also interacts with the transforming growth factor-beta signaling molecule SARA (Smad anchor for receptor activation), eukaryotic initiation factor 4G, and an E3 ubiquitinase that regulates its stability in splicing factor containing nuclear speckles. The encoded protein may function in various biological and pathological processes including spermatogenesis, cell signaling and transcription regulation, formation of stress granules during translation arrest, RNA splicing, and pathogenesis of multiple myeloma.
Entrez Gene ID
9802
UniProt ID
Q15038
Alternative Names
DAZ Associated Protein 2; Proline-Rich Transcript, Brain-Expressed Protein; Deleted In Azoospermia Associated Protein 2; Deleted In Azoospermia-Associated Protein 2; Proline-Rich Transcript In Brain; DAZ-Associated Protein 2; KIAA0058; PRTB;
Cellular Location
Nucleus; Cytoplasm. Predominantly nuclear in macrophages, stimulation of IL17RB with its ligand IL17E induces accumulation in the cytoplasm.
PTM
Ubiquitinated by SMURF2, leading to proteasomal degradation.
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For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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