Mouse Anti-DBX2 Antibody (1D8) (CBMAB-0275-YC)

Provided herein are mouse monoclonal antibodies against Human DBX2. The antibody clone 1D8 can be used for immunoassay techniques, such as IP and MA.
See all DBX2 antibodies

Datasheet

Summary

Host Animal

Mouse

Specificity

Human

Clone

1D8

Antibody Isotype

IgG2b

Application

IP, MA

Basic Information

Immunogen

Recombinant protein

Specificity

Human

Antibody Isotype

IgG2b

Application Notes

The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Format

Supernatant

Storage

Store at 4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.

Target

Full Name

DBX2

Introduction

DBX2 (developing brain homeobox 2) also known as developing brain homeobox protein 2, is a protein that in humans is encoded by the DBX2 gene. GO annotations related to this gene include sequence-specific DNA binding. An important paralog of this gene is HHEX.

Entrez Gene ID

440097

UniProt ID

Q6ZNG2

Alternative Names

Developing Brain Homeobox 2; Developing Brain Homeobox Protein 2

Biological Process

Regulation of transcription by RNA polymerase II Source: GO_Central

Cellular Location

Nucleus

References

He, R., Zhang, X., & Ding, L. (2022). DBX2 promotes glioblastoma cell proliferation by regulating REST expression. Current pharmaceutical biotechnology.

Zhang, X., Wang, Y., Zhao, S., Qin, Q., Zhang, M., Jiang, Y., ... & Li, H. (2021). Low expression of developing brain homeobox 2 (Dbx2) may serve as a biomarker to predict poor prognosis in endometrial cancer. American Journal of Translational Research, 13(5), 4738.

Beccari, L., Jaquier, G., Lopez‐Delisle, L., Rodriguez‐Carballo, E., Mascrez, B., Gitto, S., ... & Duboule, D. (2021). Dbx2 regulation in limbs suggests inter TAD sharing of enhancers. Developmental Dynamics, 250(9), 1280-1299.

Hu, Y. T., Li, B. F., Zhang, P. J., Wu, D., Li, Y. Y., Li, Z. W., ... & Zhu, X. (2019). Dbx2 exhibits a tumor-promoting function in hepatocellular carcinoma cell lines via regulating Shh-Gli1 signaling. World Journal of Gastroenterology, 25(8), 923.

Lupo, G., Nisi, P. S., Esteve, P., Paul, Y. L., Novo, C. L., Sidders, B., ... & Rugg‐Gunn, P. J. (2018). Molecular profiling of aged neural progenitors identifies Dbx2 as a candidate regulator of age‐associated neurogenic decline. Aging Cell, 17(3), e12745.

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Protocols

Please try the standard protocols which include: protocols, troubleshooting and guide.

Enzyme-linked Immunosorbent Assay (ELISA)
Flow Cytometry
Immunofluorescence (IF)
Immunohistochemistry (IHC)
Immunoprecipitation (IP)
Western Blot (WB)
Enzyme Linked Immunospot (ELISpot)
Proteogenomic
Other Protocols

Associated Products

Related Products

Mouse Anti-DBX2 Recombinant Antibody (R359.1.1E4)

Mouse Anti-DBX2 Antibody (1E4)

Mouse Anti-DBX2 Antibody (1E5)

Rabbit Anti-DBX2 Monoclonal Antibody (EPR12633(B))

Mouse Anti-DBX2 Recombinant Antibody (R359.1.1D8)

Isotype control

For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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