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Mouse Anti-DDX47 Recombinant Antibody (2255C2) (CBMAB-D0581-YC)

Provided herein is a Mouse monoclonal antibody, which binds to DEAD-Box Helicase 47 (DDX47). The antibody can be used for immunoassay techniques, such as Dot.
See all DDX47 antibodies

Summary

Host Animal
Mouse
Specificity
Human
Clone
2255C2
Antibody Isotype
IgG1
Application
Dot

Basic Information

Specificity
Human
Antibody Isotype
IgG1
Clonality
Monoclonal
Application Notes
The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Storage
Store at 4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.

Target

Full Name
DEAD (Asp-Glu-Ala-Asp) box polypeptide 47
Introduction
DDX47 belongs to the DEAD box protein family. DEAD box proteins, characterized by the conserved motif Asp-Glu-Ala-Asp (DEAD), are putative RNA helicases. They are implicated in a number of cellular processes involving alteration of RNA secondary structure, such as translation initiation, nuclear and mitochondrial splicing, and ribosome and spliceosome assembly. Based on their distribution patterns, some members of this family are believed to be involved in embryogenesis, spermatogenesis, and cellular growth and division. The protein encoded by this gene can shuttle between the nucleus and the cytoplasm, and has an RNA-independent ATPase activity. Two alternatively spliced transcript variants encoding distinct isoforms have been found for this gene.
Entrez Gene ID
51202
UniProt ID
Q9H0S4
Alternative Names
DEAD-Box Helicase 47; DEAD (Asp-Glu-Ala-Asp) Box Polypeptide 47; DEAD Box Protein 47; Probable ATP-Dependent RNA Helicase DDX47; DEAD Box Polypeptide 47; E4-DEAD Box Protein; EC 3.6.4.13;
Function
Involved in apoptosis. May have a role in rRNA processing and mRNA splicing. Associates with pre-rRNA precursors.
Biological Process
Extrinsic apoptotic signaling pathway via death domain receptors Source: UniProtKB
mRNA processing Source: UniProtKB-KW
RNA splicing Source: UniProtKB
rRNA processing Source: UniProtKB
Cellular Location
Nucleolus. Localizes in the nucleolar-organizing region during ribosome biogenesis.
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For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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