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Recombinant Mouse Anti-dlc Recombinant Antibody (zdc2) (CBMAB-XB0359-YC)

Provided herein is a Mouse Recombinant Antibody against DeltaC. The antibody can be used for immunoassay techniques, such as ELISA, FC, IHC, IF, WB.
See all dlc antibodies
Published Data

Summary

Host Animal
Mouse
Specificity
Zebrafish
Clone
zdc2
Antibody Isotype
IgG2a
Application
ELISA, FC, IHC, IF, WB

Basic Information

Immunogen
Extracellular region of zebrafish DeltaC protein
Specificity
Zebrafish
Antibody Isotype
IgG2a
Clonality
Monoclonal
Application Notes
The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Storage
Store at 4°C short term (1-2 weeks). Aliquot and store at-20°C long term. Avoid repeated freeze/thaw cycles.

Target

Full Name
DeltaC
Introduction
Acts as a ligand for Notch receptors and is involved in somitogenesis. Can activate Notch receptors. Required in somite segmentation to keep the oscillations of neighboring presomitic mesoderm cells synchronized.
Entrez Gene ID
UniProt ID
Alternative Names
DeltaC
Function
Acts as a ligand for Notch receptors and is involved in somitogenesis. Can activate Notch receptors. Required in somite segmentation to keep the oscillations of neighboring presomitic mesoderm cells synchronized.
Biological Process
Arterial endothelial cell differentiation Source: ZFIN
Blood vessel morphogenesis Source: ZFIN
Dorsal aorta development Source: ZFIN
Hematopoietic progenitor cell differentiation Source: ZFIN
Hematopoietic stem cell differentiation Source: ZFIN
Negative regulation of Notch signaling pathway Source: GO_Central
Neuron development Source: ZFIN
Notch signaling pathway Source: ZFIN
Sclerotome development Source: ZFIN
Somite specification Source: ZFIN
Somitogenesis Source: ZFIN
Ventral spinal cord interneuron differentiation Source: ZFIN
Cellular Location
Membrane
Topology
Extracellular: 21-511
Helical: 512-532
Cytoplasmic: 533-664
PTM
Ubiquitinated by mib, leading to its endocytosis and subsequent degradation.
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For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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