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Mouse Anti-DYNLT3 Recombinant Antibody (10A3-CA-81) (CBMAB-D2012-YC)

Provided herein is a Mouse monoclonal antibody, which binds to Dynein Light Chain Tctex-Type 3 (DYNLT3). The antibody can be used for immunoassay techniques, such as WB, IHC.
See all DYNLT3 antibodies

Summary

Host Animal
Mouse
Specificity
Human, Mouse, Rat
Clone
10A3-CA-81
Antibody Isotype
IgG2a
Application
WB, IHC

Basic Information

Immunogen
Full-length recombinant human DYNLT3 protein
Specificity
Human, Mouse, Rat
Antibody Isotype
IgG2a
Clonality
Monoclonal
Application Notes
The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Storage
Store at 4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.

Target

Full Name
Dynein Light Chain Tctex-Type 3
Introduction
DYNLT3 belongs to a subclass of dynein light chains. The encoded protein homodimerizes and forms the light chain component of the cytoplasmic dynein motor protein complex. This protein may be important for binding dynein to specific cargos including the spindle checkpoint protein BUB3. This protein may also function independently of dynein as a transcriptional modulator.
Entrez Gene ID
Human6990
Mouse67117
Rat363448
UniProt ID
HumanP51808
MouseP56387
RatQ5XI90
Alternative Names
Dynein Light Chain Tctex-Type 3; Protein 91/23; TCTE1L; T-Complex-Associated-Testis-Expressed 1-Like; T-Complex-Associated Testis-Expressed 1-Like; TCTEX1L; TCTE1XL; RP3;
Research Area
Acts as one of several non-catalytic accessory components of the cytoplasmic dynein 1 complex that are thought to be involved in linking dynein to cargos and to adapter proteins that regulate dynein function. Cytoplasmic dynein 1 acts as a motor for the intracellular retrograde motility of vesicles and organelles along microtubules. Probably binds BUB3 as part of transport cargo. Required for the efficient progression through mitosis (By similarity).
Biological Process
Cell cycle Source: UniProtKB-KW
Cell division Source: UniProtKB-KW
Positive regulation of mitotic cell cycle Source: Ensembl
Regulation of mitotic cell cycle Source: UniProtKB
Cellular Location
Nucleus; Cytoskeleton; Kinetochore. Colocalizes with BUB3 at kinetochores specifically during prometaphase.
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For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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