FC, ELISA, IF, IHC-Fr, CyTOF
Human eosinophils from a patient with hypereosinophilic syndrome
Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.
This gene is a member of the peroxidase gene family and is expressed in eosinophils. The encoded preproprotein is proteolytically processed into covalently attached heavy and light chains to form the mature enzyme, which functions as an oxidant. The enzyme is released at sites of parasitic infection or allergen stimulation to mediate lysis of protozoa or parasitic worms. The gene is found in a gene cluster with other peroxidase genes on chromosome 17. Mutations in this gene result in eosinophil peroxidase deficiency.
Eosinophil Peroxidase; EC 220.127.116.11; EPO; EPP; EC 1.11.1; EPX-PEN; EPXD; EPER