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Mouse Anti-FADD Recombinant Antibody (CBXF-0262) (CBMAB-F2179-CQ)

This product is a mouse antibody that recognizes FADD. The antibody CBXF-0262 can be used for immunoassay techniques such as: WB.
Host Species
Mouse
Application
WB
Antibody Isotype
IgG
Cross Reactivity
Human
Clone
CBXF-0262
Format
Liquid
Storage
Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.
Introduction
The protein encoded by this gene is an adaptor molecule that interacts with various cell surface receptors and mediates cell apoptotic signals. Through its C-terminal death domain, this protein can be recruited by TNFRSF6/Fas-receptor, tumor necrosis factor receptor, TNFRSF25, and TNFSF10/TRAIL-receptor, and thus it participates in the death signaling initiated by these receptors. Interaction of this protein with the receptors unmasks the N-terminal effector domain of this protein, which allows it to recruit caspase-8, and thereby activate the cysteine protease cascade. Knockout studies in mice also suggest the importance of this protein in early T cell development.
Alternative Name
Fas Associated Via Death Domain; Fas-Associating Death Domain-Containing Protein; Growth-Inhibiting Gene 3 Protein; Fas-Associating Protein With Death Domain; Fas (TNFRSF6)-Associated Via Death Domain; Mediator Of Receptor-Induced Toxicity;
Entrez Gene ID
UniProt ID
Cat CBMAB-F2179-CQ
Conjugates
Size
Price $
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