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Rabbit Anti-GNE Recombinant Antibody (CBLG1-2857) (CBMAB-G4141-LY)

This product is antibody recognizes GNE. The antibody CBLG1-2857 immunoassay techniques such as: WB.
Host Animal
Rabbit
Application
WB
Antibody Isotype
IgG
Cross Reactivity
Mouse, Rat, Human
Clone
CBLG1-2857
Format
Liquid
Storage
Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freezethaw cycles.
Introduction
The protein encoded by this gene is a bifunctional enzyme that initiates and regulates the biosynthesis of N-acetylneuraminic acid (NeuAc), a precursor of sialic acids. It is a rate-limiting enzyme in the sialic acid biosynthetic pathway. Sialic acid modification of cell surface molecules is crucial for their function in many biologic processes, including cell adhesion and signal transduction. Differential sialylation of cell surface molecules is also implicated in the tumorigenicity and metastatic behavior of malignant cells. Mutations in this gene are associated with sialuria, autosomal recessive inclusion body myopathy, and Nonaka myopathy. Alternative splicing of this gene results in transcript variants encoding different isoforms. [provided by RefSeq, Jul 2008]
Cat CBMAB-G4141-LY
Conjugates
Size
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