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Rabbit Anti-H3 (phospho S10) Recombinant Antibody (MA066YC) (CBMAB-MA330-YC)

Provided herein is a Rabbit monoclonal antibody against Histone H3 (phospho S10). The antibody can be used for immunoassay techniques, such as Peptide Array, ChIP, IHC-P, WB, ICC, IF. And it gave a positive signal in HeLa and NIH/3T3 treated with 15µg/ml Colcemid for 12 hours whole cell lysates and Human placenta, mouse colon and rat colon tissues.
See all H3 (phospho S10) antibodies

Summary

Host Animal
Rabbit
Specificity
Human, Mouse, Rat
Clone
MA066YC
Antibody Isotype
IgG
Application
Peptide Array, ChIP, IHC-P, WB, ICC, IF

Basic Information

Immunogen
Synthetic peptide within Human Histone H3 aa 1-100 (phospho S10)
Specificity
Human, Mouse, Rat
Antibody Isotype
IgG
Clonality
Monoclonal
Application Notes
The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Buffer
0.01% Sodium azide, 59% PBS, 40% Glycerol and 0.05% BSA
Purity
ChIP Grade
Storage
Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C long term. Avoid freeze / thaw cycle.

Target

Full Name
Histone H3 (phospho S10)
Introduction
Histone H3 is one of the five main histone proteins involved in the structure of chromatin in eukaryotic cells. Featuring a main globular domain and a long N-terminal tail, H3 is involved with the structure of the nucleosomes of the 'beads on a string' structure. Histone proteins are highly post-translationally modified however Histone H3 is the most extensively modified of the five histones. The term "Histone H3" alone is purposely ambiguous in that it does not distinguish between sequence variants or modification state. Histone H3 is an important protein in the emerging field ofepigenetics, where its sequence variants and variable modification states are thought to play a role in the dynamic and long term regulation of genes.
Alternative Names
Histone H3 (phospho S10)
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For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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