|  

Mouse Anti-IL15 Recombinant Antibody (1A5) (CBMAB-A4346-LY)

The product is antibody recognizes IL15. The antibody 1A5 immunoassay techniques such as: ELISA.
Host Animal
Mouse
Application
ELISA
Immunogen
IL15 (NP_000576, 49 a.a. ~ 162 a.a) full length recombinant protein.
Antibody Isotype
IgG2a, κ
Specificity
Human
Cross Reactivity
Human
Clone
1A5
Format
Liquid
Storage
Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freezethaw cycles.
Introduction
The protein encoded by this gene is a cytokine that regulates T and natural killer cell activation and proliferation. This cytokine and interleukine 2 share many biological activities. They are found to bind common hematopoietin receptor subunits, and may compete for the same receptor, and thus negatively regulate each other's activity. The number of CD8+ memory cells is shown to be controlled by a balance between this cytokine and IL2. This cytokine induces the activation of JAK kinases, as well as the phosphorylation and activation of transcription activators STAT3, STAT5, and STAT6. Studies of the mouse counterpart suggested that this cytokine may increase the expression of apoptosis inhibitor BCL2L1/BCL-x(L), possibly through the transcription activation activity of STAT6, and thus prevent apoptosis. Two alternatively spliced transcript variants of this gene encoding the same protein have been reported. [provided by RefSeq]
Alternative Name
IL-15; MGC9721
Entrez Gene ID
Cat CBMAB-A4346-LY
Conjugates
Size
  ADD TO CART