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Mouse Anti-IL4R Recombinant Antibody (CBYY-I0955) (CBMAB-I2123-YY)

This product is Mouse antibody that recognizes IL4R . The antibody CBYY-I0955 can be used for immunoassay techniques such as: ELISA
Host Animal
Mouse
Application
ELISA
Clone
CBYY-I0955
Format
Liquid
Storage
Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.
Introduction
This gene encodes the alpha chain of the interleukin-4 receptor, a type I transmembrane protein that can bind interleukin 4 and interleukin 13 to regulate IgE production. The encoded protein also can bind interleukin 4 to promote differentiation of Th2 cells. A soluble form of the encoded protein can be produced by proteolysis of the membrane-bound protein, and this soluble form can inhibit IL4-mediated cell proliferation and IL5 upregulation by T-cells. Allelic variations in this gene have been associated with atopy, a condition that can manifest itself as allergic rhinitis, sinusitus, asthma, or eczema. Polymorphisms in this gene are also associated with resistance to human immunodeficiency virus type-1 infection. Alternate splicing results in multiple transcript variants.
Alternative Name
Interleukin 4 Receptor
Entrez Gene ID
UniProt ID
Cat CBMAB-I2123-YY
Conjugates
Size
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