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Mouse Anti-Klra8 Recombinant Antibody (3D10) (CBMAB-L2962-YJ)

Provided herein is a Mouse monoclonal antibody, which binds to Killer Cell Lectin-Like Receptor Subfamily A Member 8 (Klra8). The antibody can be used for immunoassay techniques, such as FC.
See all Klra8 antibodies
Published Data
Fig.1 Flow cytometric analysis of Ly49H‐expressing HD12 cells mixed (1:1) with parental C1498 cells (left column), C1498‐m157wt cells (middle column), or C1498‐m157‐N178,187,213,267N cells expressing unglycosylated m157 (right column) at the indicated times of coincubation.
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Fig.2 Splenic NK cells (DX5+ TCR-) from B6 WT and DAP10-deficient mice infected 6 d prior with MCMV-Smith were sorted to>93% purity and incubated on Ly49H mAb-coated plates for 0–20 min.
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Fig.3 Ly49H expression on NK1.1+ cells from NZ mice.
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Fig.4 Fresh B6, NZW, NZB, and BALB/c splenocytes (mAb 2.4G2 blocked) were labeled with anti-NK1.1 PE and either anti-Ly49H FITC or m157-Ig plus anti-human IgG-FITC and analyzed by flow cytometry (105 total events per sample).
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Summary

Host Animal
Mouse
Specificity
Mouse
Clone
3D10
Antibody Isotype
IgG1, κ
Application
FC

Basic Information

Immunogen
Mouse Ly-49A/H Transfected Cell Line.
Specificity
Mouse
Antibody Isotype
IgG1, κ
Clonality
Monoclonal
Application Notes
The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Buffer
PBS, pH 7.4
Storage
Store at 4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.

Target

Full Name
Killer Cell Lectin-Like Receptor, Subfamily A, Member 8
Introduction
It is a receptor on natural killer (NK) cells for class I MHC.
Entrez Gene ID
16639
UniProt ID
Q60682
Alternative Names
Cmv1; Cmv-1; Ly49h; Ly49u<129>; killer cell lectin-like receptor 8; T-cell surface glycoprotein Ly-49H; cytomegalovirus resistance 1; ly-49h; lymphocyte antigen 49h
Function
Receptor on natural killer (NK) cells for class I MHC.
Biological Process
Cell adhesionIEA:UniProtKB-KW
Response to virusManual Assertion Based On ExperimentIDA:MGI
Cellular Location
Cell membrane
Topology
Cytoplasmic: 1-44
Helical: 45-66
Extracellular: 67-266
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For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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