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Mouse Anti-CERS4 Recombinant Antibody (7D5) (CBMAB-A4870-LY)

The product is antibody recognizes LASS4. The antibody 7D5 immunoassay techniques such as: sELISA, ELISA.
See all CERS4 antibodies

Summary

Host Animal
Mouse
Specificity
Human
Clone
7D5
Antibody Isotype
IgG2a, κ
Application
sELISA, ELISA

Basic Information

Immunogen
LASS4 (NP_078828, 57 a.a. ~ 139 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
Specificity
Human
Antibody Isotype
IgG2a, κ
Clonality
Monoclonal
Application Notes
The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Format
Liquid
Purity
> 95% Purity determined by SDS-PAGE.
Storage
Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freezethaw cycles.

Target

Full Name
Ceramide Synthase 4
Entrez Gene ID
UniProt ID
Alternative Names
CerS4; FLJ12089; Trh1
Function
Ceramide synthase that catalyzes formation of ceramide from sphinganine and acyl-CoA substrates, with high selectivity toward long and very-long chains (C18:0-C22:0) as acyl donor.
Biological Process
Ceramide biosynthetic process Source: UniProtKB
Sphingolipid biosynthetic process Source: Reactome
Cellular Location
Endoplasmic reticulum membrane
Topology
Lumenal: 1-31
Helical: 32-52
Helical: 140-160
Helical: 179-199
Helical: 209-229
Helical: 260-280
Helical: 304-324
Cytoplasmic: 325-394
PTM
Phosphorylated at the C-terminus by CK2.
N-glycosylated.
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For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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