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Mouse Anti-LPHN1 Recombinant Antibody (4E12) (CBMAB-A5054-LY)

The product is antibody recognizes LPHN1. The antibody 4E12 immunoassay techniques such as: WB, ELISA.
Host Species
Mouse
Application
WB, ELISA
Immunogen
LPHN1 (AAH19928, 1 a.a. ~ 201 a.a) full-length recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
Antibody Isotype
IgG2a, κ
Specificity
Human
Clone
4E12
Format
Liquid
Storage
Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freezethaw cycles.
Introduction
This gene encodes a member of the latrophilin subfamily of G-protein coupled receptors (GPCR). Latrophilins may function in both cell adhesion and signal transduction. In experiments with non-human species, endogenous proteolytic cleavage within a cysteine-rich GPS (G-protein-coupled-receptor proteolysis site) domain resulted in two subunits (a large extracellular N-terminal cell adhesion subunit and a subunit with substantial similarity to the secretin/calcitonin family of GPCRs) being non-covalently bound at the cell membrane. Latrophilin-1 has been shown to recruit the neurotoxin from black widow spider venom, alpha-latrotoxin, to the synapse plasma membrane. Alternative splicing results in multiple variants encoding distinct isoforms
Alternative Name
CIRL1; CL1; LEC2
Entrez Gene ID
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For Research Use Only. Not For Clinical Use.
Cat CBMAB-A5054-LY
Conjugates
Size
Price $
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Second antibody and isotype control