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Mouse Anti-M6PR Recombinant Antibody (22d4) (CBMAB-0099-CN)

This product is a mouse antibody that recognizes M6PR of bovine. The antibody 22d4 can be used for immunoassay techniques such as: IF, IP, WB.
Host Species
Mouse
Application
IF, IP, WB
Immunogen
Mannose 6-phosphate receptors mix (MPR) purified from bovine calf liver
Antibody Isotype
IgG2b, κ
Specificity
Bovine, Human
Clone
22d4
Format
Liquid
Storage
Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.
Introduction
This gene encodes a member of the P-type lectin family. P-type lectins play a critical role in lysosome function through the specific transport of mannose-6-phosphate-containing acid hydrolases from the Golgi complex to lysosomes. The encoded protein functions as a homodimer and requires divalent cations for ligand binding. Lysosomal enzymes bearing phosphomannosyl residues bind specifically to mannose-6-phosphate receptors in the Golgi apparatus and the resulting receptor-ligand complex is transported to an acidic prelyosomal compartment where the low pH mediates the dissociation of the complex.
Alternative Name
CDMPR; CD-MPR
Entrez Gene ID
UniProt ID
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For research use only. Not intended for any clinical use.
Cat CBMAB-0099-CN
Conjugates
Size
Price $
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Second antibody and isotype control