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Rabbit Anti-Phospho-CFL1 (Ser3) Recombinant Antibody (77G2) (CBMAB-CP0341-LY)

The product is antibody recognizes Phospho-CFL1 (Ser3). The antibody 77G2 immunoassay techniques such as: WB,IF (ICC).
Host Animal
Rabbit
Application
WB, IF (ICC)
Immunogen
Monoclonal antibody is produced by immunizing animals with a synthetic phosphopeptide corresponding to residues surrounding Ser3 of human cofilin.
Antibody Isotype
IgG
Cross Reactivity
Human, Mouse, Rat, Monkey, Bovine
Clone
77G2
Format
Liquid
Storage
Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freezethaw cycles.
Introduction
The protein encoded by this gene can polymerize and depolymerize F-actin and G-actin in a pH-dependent manner. Increased phosphorylation of this protein by LIM kinase aids in Rho-induced reorganization of the actin cytoskeleton. Cofilin is a widely distributed intracellular actin-modulating protein that binds and depolymerizes filamentous F-actin and inhibits the polymerization of monomeric G-actin in a pH-dependent manner. It is involved in the translocation of actin-cofilin complex from cytoplasm to nucleus.[supplied by OMIM, Apr 2004]
Alternative Name
Cofilin 1; Cofilin; Non-Muscle Isoform; Cofilin 1 (Non-Muscle); 18 KDa Phosphoprotein; P18; CFL;
Entrez Gene ID
UniProt ID