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Rabbit Anti-Phospho-EIF2S1 (Ser51) Recombinant Antibody (119A11) (CBMAB-CP0556-LY)

The product is antibody recognizes Phospho-EIF2S1 (Ser51). The antibody 119A11 immunoassay techniques such as: WB,IP,IHC-P.
Host Animal
Rabbit
Application
WB, IP, IHC-P
Immunogen
Monoclonal antibody is produced by immunizing animals with a synthetic phosphopeptide corresponding to residues surrounding Ser51 of human eIF2alpha.
Antibody Isotype
IgG
Cross Reactivity
Human, Mouse, Rat, Monkey, D. melanogaster
Clone
119A11
Format
Liquid
Storage
Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freezethaw cycles.
Introduction
The translation initiation factor EIF2 catalyzes the first regulated step of protein synthesis initiation, promoting the binding of the initiator tRNA to 40S ribosomal subunits. Binding occurs as a ternary complex of methionyl-tRNA, EIF2, and GTP. EIF2 is composed of 3 nonidentical subunits, the 36-kD EIF2-alpha subunit (EIF2S1), the 38-kD EIF2-beta subunit (EIF2S2; MIM 603908), and the 52-kD EIF2-gamma subunit (EIF2S3; MIM 300161). The rate of formation of the ternary complex is modulated by the phosphorylation state of EIF2-alpha (Ernst et al., 1987 [PubMed 2948954]).[supplied by OMIM, Feb 2010]
Alternative Name
Eukaryotic Translation Initiation Factor 2 Subunit Alpha; Eukaryotic Translation Initiation Factor 2; Subunit 1 Alpha; 35kDa; EIF-2-Alpha; EIF-2alpha; EIF-2A; EIF2A;
Entrez Gene ID
UniProt ID
Cat CBMAB-CP0556-LY
Conjugates
Size
Price $
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