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Mouse Anti-Phospho-ESR1 (Ser118) Recombinant Antibody (16J4) (CBMAB-CP0623-LY)

The product is antibody recognizes Phospho-ESR1 (Ser118). The antibody 16J4 immunoassay techniques such as: WB,IHC-P.
Host Animal
Mouse
Application
WB, IHC-P
Immunogen
Monoclonal antibody is produced by immunizing animals with a synthetic phosphopeptide corresponding to residues surrounding Ser118 of human ER α.
Antibody Isotype
IgG2b
Cross Reactivity
Human
Clone
16J4
Format
Liquid
Storage
Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freezethaw cycles.
Introduction
This gene encodes an estrogen receptor, a ligand-activated transcription factor composed of several domains important for hormone binding, DNA binding, and activation of transcription. The protein localizes to the nucleus where it may form a homodimer or a heterodimer with estrogen receptor 2. Estrogen and its receptors are essential for sexual development and reproductive function, but also play a role in other tissues such as bone. Estrogen receptors are also involved in pathological processes including breast cancer, endometrial cancer, and osteoporosis. Alternative promoter usage and alternative splicing result in dozens of transcript variants, but the full-length nature of many of these variants has not been determined. [provided by RefSeq, Mar 2014]
Alternative Name
Estrogen Receptor 1; Nuclear Receptor Subfamily 3 Group A Member 1; Oestrogen Receptor Alpha; Estradiol Receptor; E2 Receptor Alpha; ER-Alpha; NR3A1; ESR; ER;
Entrez Gene ID
UniProt ID
Cat CBMAB-CP0623-LY
Conjugates
Size
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